Results 331 to 340 of about 2,209,671 (402)
Kinetics for Drug Discovery: an industry-driven effort to target drug residence time
Drug Discovery Today, 2017 Doris A Schuetz +2 more
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Kinetics of Drug Binding and Residence Time.
Annual review of physical chemistry (Print), 2019The kinetics of drug binding and unbinding is assuming an increasingly crucial role in the long, costly process of bringing a new medicine to patients. For example, the time a drug spends in contact with its biological target is known as residence time ...
Mattia Bernetti +3 more
semanticscholar +1 more source
Variability in organic carbon reactivity across lake residence time and trophic gradients
Nature Geoscience, 2017Chris D Evans +2 more
exaly +2 more sources
The Annals of Thoracic Surgery, 1971
Abstract Residency training programs in thoracic surgery are expensive apprenticeships based in a hospital. Our present thoracic surgery residency programs evolved from nineteenth century German models, which were transferred to this country with the founding of The Johns Hopkins Hospital. Dr. William S.
openaire +2 more sources
Abstract Residency training programs in thoracic surgery are expensive apprenticeships based in a hospital. Our present thoracic surgery residency programs evolved from nineteenth century German models, which were transferred to this country with the founding of The Johns Hopkins Hospital. Dr. William S.
openaire +2 more sources
Target engagement and drug residence time can be observed in living cells with BRET
Nature Communications, 2015 The therapeutic action of drugs is predicated on their physical engagement with cellular targets. Here we describe a broadly applicable method using bioluminescence resonance energy transfer (BRET) to reveal the binding characteristics of a drug with ...
Matthew B Robers +2 more
exaly +2 more sources
Where do Golgi residents reside?
Trends in Cell Biology, 2000Ever since Camillo Golgi's initial description, over a century ago, of the organelle that would eventually bear his name, scientists have sought to understand how this beautifully organized stack of membranes functions inside the eukaryotic cell. The function of the Golgi as a central player in the anterograde traffic of secretory proteins is well ...
openaire +2 more sources
Pediatrics, 1988
In the absence of confirmatory evidence, one can only sense that the lives of residents have become increasingly stressful since the late 1950s. Certainly residency stress is receiving more attention in the medical literature.1-4 An excellent conference on stress in pediatric housestaff training sponsored by the Study Group on Pediatric Education and ...
openaire +2 more sources
In the absence of confirmatory evidence, one can only sense that the lives of residents have become increasingly stressful since the late 1950s. Certainly residency stress is receiving more attention in the medical literature.1-4 An excellent conference on stress in pediatric housestaff training sponsored by the Study Group on Pediatric Education and ...
openaire +2 more sources
Co-Residence Patterns in Hunter-Gatherer Societies Show Unique Human Social Structure
Science, 2011Robert S Walker +2 more
exaly +2 more sources
The Journal of Bone and Joint Surgery-American Volume, 2000
R. C. is an orthopaedic resident in a teaching program. At the orthopaedic clinic, he examines an elderly, otherwise healthy patient who requires a total hip replacement. He presents the patient to his covering attending physician, who agrees to supervise the joint replacement surgery. The resident discusses the surgery with the patient. The procedure,
J D, Capozzi, R, Rhodes
openaire +2 more sources
R. C. is an orthopaedic resident in a teaching program. At the orthopaedic clinic, he examines an elderly, otherwise healthy patient who requires a total hip replacement. He presents the patient to his covering attending physician, who agrees to supervise the joint replacement surgery. The resident discusses the surgery with the patient. The procedure,
J D, Capozzi, R, Rhodes
openaire +2 more sources
Resident-to-Resident Aggression in Private Seniors’ Residences
GeroPsych, 2023Abstract: Resident-to-resident aggression (RRA) is a globally-recognized problem in long-term care centers which is presently understudied among private seniors’ residences (PSRs) for independent and semi-independent older adults. This research documents the manifestations of RRA in PSRs in Québec and identifies the need to develop a program promoting
Marie-Chantal Falardeau +3 more
openaire +1 more source