Results 61 to 70 of about 445,799 (319)
This article presents two inventories of the Lviv Archbishop of the Latin Rite in Obroszyn in the form of a source edition. They were analysed and labelled with back matter.
Grzegorz Chajko
doaj +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Taxation of Non – Resident Legal Entities in Romania. Case: Rmms vs. Anaf Brăila
The taxation of non - resident economic entities supposes the establishment of an administrative framework as fair, efficient, effective and comprehensible as possible, fact due to the multifaceted nature of the concept of profits generated by an ...
Dumiter Professor Florin +1 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
RESEARCH OF STUDENTS' ORIENTATIONS REGARDING INTERNATIONAL MIGRATION
The purpose of the article is to identify and compare the essential characteristics of migration attitudes among Ukrainian and Polish students, and to outline trends in their development in the future. Methodology.
Oksana Bulyk
doaj +1 more source
Museums in former residences: castles, palaces and manor houses
The article concerns former residences in Poland and their contemporary use as museums. The authors present the history of Polish residences, the development of museums in castles, palaces and manor houses, their spatial distribution and the relations ...
Beata Krakowiak, Jolanta Latosińska
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Introduction: Growing older is a universal process. The exact boundaries of old age cannot be determined because definitions vary from nation to nation. Aging is a complicated and irreversible process.
A. M. Arun Vineeth +3 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source

