Results 31 to 40 of about 291,873 (266)

CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS AND SPATIAL DISTRIBUTION OF INFANT MORTALITY IN NORTHEASTERN BRAZIL, IN THE PERIOD 2008-2011 [PDF]

Revista Gestão & Saúde, 2014
Objective: To characterize infant mortality in Northeastern Brazil. Method: A descriptive-retrospective study of time series with a quantitative approach, which analyzed cases reported to the Notifiable Diseases Information System (SINAN) in ...
Débora Regina Marques Barbosa , Manoel Guedes de Almeida   +1 more
doaj  

Neighborhood characteristics and dementia symptomology among community-dwelling older adults with Alzheimer’s disease

Frontiers in Aging Neuroscience, 2022
BackgroundNeuropsychiatric symptoms (NPSs) lead to myriad poor health outcomes among individuals with Alzheimer’s disease (AD). Prior studies have observed associations between the various aspects of the home environment and NPSs, but macro-level ...
Dana M. Alhasan, Matthew C. Lohman, Jana A. Hirsch, Maggi C. Miller, Bo Cai, Chandra L. Jackson, Chandra L. Jackson   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The association between living arrangements and health-related quality of life in Korean older people: a nationwide repeated cross-sectional study [PDF]

Osong Public Health and Research Perspectives
Objectives This study investigated the association between living arrangements and health-related quality of life (HRQoL) in older people. Methods A secondary analysis was conducted of 6,153 participants (aged ≥60 years) from the seventh Korean National ...
Eunok Park, Philip Larkin, Zee-A Han
doaj   +1 more source

Basic mobility, accidental falls, and lifetime physical activity among rural and urban community-dwelling older adults: a population-based study in Northern Iceland

International Journal of Circumpolar Health, 2022
The objective of this research was to investigate late-life physical functioning and lifetime history of physical activity (PA) among older adults in rural and urban Arctic communities.
Solveig A Arnadottir, Lara Einarsdottir, Arun K Sigurdardottir   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Neighborhood and Individual Sociodemographic Characteristics Associated with Disparities in Adult Obesity and Perceptions of the Home Food Environment

Health Equity, 2017
Purpose: Multiple studies have demonstrated significant disparities in the relationship between individual sociodemographic characteristics and risk of overweight or obesity. However, little information is available for assessing the complex associations
Michael T. Halpern, Michael T. Halpern, Laura C. Arena, Rachel A. Royce, Robin E. Soler, Breda Munoz, Caitlin M. Hennessy   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The role of neighborhood inequalities on diabetes prevention care: a mini-review

Frontiers in Clinical Diabetes and Healthcare, 2023
An emerging research niche has focused on the link between social determinants of health and diabetes mellitus, one of the most prevalent non-communicable diseases in modern society.
Francesco Frigerio, Luca Muzzioli, Alessandro Pinto, Lorenzo Maria Donini, Eleonora Poggiogalle   +4 more
doaj   +1 more source