Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Nonchaotic Stagnant Motion in a Marginal Quasiperiodic Gradient System
, 2008 A one-dimensional dynamical system with a marginal quasiperiodic gradient is presented as a mathematical extension of a nonuniform oscillator. The system exhibits a nonchaotic stagnant motion, which is reminiscent of intermittent chaos.
A. Barone +12 more
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Residence time distribution of gas flows in microreactors: Measurement and model comparison [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011) +7 more
core
Reversible lysine-targeted probes reveal residence time-based kinase selectivity
Nature Chemical Biology, 2022 Tangpo Yang +12 more
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Influence of the meandering channel geometry on the thermo-hydraulic performances of an intensified heatexchanger/reactor [PDF]
, 2013 In the global context of process intensification, heat exchanger/reactors are promising apparatuses to implement exothermic chemical syntheses. However, unlike heat exchange processes, the implementation of chemical syntheses requires to control the ...
Anxionnaz-Minvielle, Zoé +3 more
core +3 more sources
DNA residence time is a regulatory factor of transcription repression
Nucleic Acids Research, 2017 Transcription comprises a highly regulated sequence of intrinsically stochastic processes, resulting in bursts of transcription intermitted by quiescence.
K. Clauss +7 more
semanticscholar +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
From Mansions to Towers: A History of Residence Halls at the University of Wisconsin-Eau Claire [PDF]
, 2012 The construction of the University of Wisconsin-Eau Claire's residence halls has generally followed that of the national trend. The school struggled to find enough funds to build residence halls in the early years.
Skeen, Mitchell A.
core +1 more source