Results 171 to 180 of about 454,936 (308)

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

Arthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein, Jennifer L. F. Lee, Evelyne Vinet, Arielle Mendel, Christian A. Pineau, Fares Kalache, Louis‐Pierre Grenier, Sasha Bernatsky   +7 more
wiley   +1 more source

Cholesterol residence time drives regulation of the G protein-coupled cholecystokinin receptor. [PDF]

Mol Pharmacol
Toufaily C, Ma Y, Barbosa ED, Harikumar KG, Wootten D, Sexton PM, Liu W, Miller LJ.   +7 more
europepmc   +1 more source

Structure-affinity and structure-residence time relationships of macrocyclic Gα_q protein inhibitors. [PDF]

iScience, 2023
Voss JH, Crüsemann M, Bartling CRO, Kehraus S, Inoue A, König GM, Strømgaard K, Müller CE.   +7 more
europepmc   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

PERRC: Protease Engineering with Reactant Residence Time Control. [PDF]

ACS Synth Biol
Nelson S, Gaza J, Ajayebi S, Masse R, Pho R, Scutero C, Martinusen S, Long L, Menezes A, Perez A, Denard C.   +10 more
europepmc   +1 more source

Understanding the burden of orofacial involvement and patient treatment preferences in systemic sclerosis: results from a large international survey

Arthritis Care &Research, Accepted Article.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc), yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprising 38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni, Lee Shapiro, Deana Gibbs, Zsuzsanna H. McMahan, Michael Hughes   +4 more
wiley   +1 more source

Structural basis of the residence time of adenosine A_2A receptor ligands revealed by NMR. [PDF]

Chem Sci
Ueda T, Tsuchida T, Kurita M, Mizumura T, Imai S, Shiraishi Y, Kofuku Y, Miyakawa S, Fukuzawa K, Takeuchi K, Shimada I.   +10 more
europepmc   +1 more source

Unraveling the Mechanism of Epichaperome Modulation by Zelavespib: Biochemical Insights on Target Occupancy and Extended Residence Time at the Site of Action. [PDF]

Biomedicines, 2023
Sharma S, Joshi S, Kalidindi T, Digwal CS, Panchal P, Lee SG, Zanzonico P, Pillarsetty N, Chiosis G.   +8 more
europepmc   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

Advanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal, Michael M. Becker, Sarah C. L. Fischer   +2 more
wiley   +1 more source

Rational Design of Ligands with Optimized Residence Time. [PDF]

ACS Pharmacol Transl Sci
Carloni P, Rossetti G, Müller CE.
europepmc   +1 more source