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Advanced Functional Materials, EarlyView.This study develops a novel atomic engineering strategy to fine‐tune the spin state of α‐Fe2O3 catalysts toward a medium‐spin state, thereby modulating peroxymonosulfate activation and selectively yielding surface‐bound radicals. Compared with free radicals, surface‐bound radicals exhibit moderated oxidation potential, extended lifespan, surface ...
Shuyu Wang +7 more
wiley +1 more source
Efficient Charge Transport in Zero‐Dimensional Perovskite for Ultrahigh‐Sensitivity X‐Ray Detection
Advanced Functional Materials, EarlyView.A novel mono‐octahedral 0D Bi‐based Dpy3Bi2I12 perovskite strengthens the internal hydrogen bonds and forms a quasi‐2D lattice, exhibits exceptional charge transport and mobility, achieving high X‐ray sensitivity and ultralow‐dose imaging, and setting a new benchmark for 0D detector performance.
Xin Song +16 more
wiley +1 more source
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Partial residence times: determining residence time composition in different subregions
Ocean Dynamics, 2019Residence time (RT) is a diagnosis widely used to quantify the water exchange rate and mass transport timescale in semi-enclosed systems. The RT focuses on only the total time a water parcel spends in a system (i.e., control region). However, for a system that consists of several subregions (e.g., sub-bays or functional zones), the RT will not include ...
Lei Lin, Zhe Liu
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The importance of binding kinetics and drug–target residence time in pharmacology
British Journal of Pharmacology, 2023A dominant assumption in pharmacology throughout the 20th century has been that in vivo target occupancy—and attendant pharmacodynamics—depends on the systemic concentration of drug relative to the equilibrium dissociation constant for the drug–target ...
K. Knockenhauer, R. Copeland
semanticscholar +1 more source
Evolution of the drug-target residence time model
Expert Opinion on Drug Discovery, 2021Introduction The pharmacological action of a drug is linked to its affinity for a specific molecular target as quantified by in vitro equilibrium measurements.
R. Copeland
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Kinetics of Drug Binding and Residence Time.
Annual review of physical chemistry (Print), 2019The kinetics of drug binding and unbinding is assuming an increasingly crucial role in the long, costly process of bringing a new medicine to patients. For example, the time a drug spends in contact with its biological target is known as residence time ...
Mattia Bernetti +3 more
semanticscholar +1 more source