Residence time distribution (RTD) revisited. [PDF]
Chem Eng Sci, 2021 Residence Time Distribution (RTD) theory is revisited and tracer technology discussed. The background of RTD following Danckwerts ideas is presented by introducing "distribution" functions for residence time, internal age and intensity function and how to experimentally obtain them with tracer techniques (curves C and F of Danckwerts).
Rodrigues AE.
europepmc +5 more sources
Development and Use of a Residence Time Distribution (RTD) Model Control Strategy for a Continuous Manufacturing Drug Product Pharmaceutical Process [PDF]
Pharmaceutics, 2022 Residence-time-distribution (RTD)-based models are key to understanding the mixing dynamics of continuous manufacturing systems. Such models can allow for material traceability throughout the process and can provide the ability for removal of non ...
Samantha Hurley +4 more
doaj +4 more sources
Inline Determination of Residence Time Distribution in Hot-Melt-Extrusion [PDF]
Pharmaceutics, 2018 In the framework of Quality-by-Design (QbD), the inline determination of process parameters or quality attributes of a product using sufficient process analytical technology (PAT) is a center piece for the establishment of continuous processes as a ...
Jens Wesholowski +2 more
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Subject-Specific Calculation of Left Atrial Appendage Blood-Borne Particle Residence Time Distribution in Atrial Fibrillation [PDF]
Frontiers in Physiology, 2021 Atrial fibrillation (AF) is the most common arrhythmia that leads to thrombus formation, mostly in the left atrial appendage (LAA). The current standard of stratifying stroke risk, based on the CHA2DS2-VASc score, does not consider LAA morphology, and ...
Soroosh Sanatkhani +7 more
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Process Design of Continuous Powder Blending Using Residence Time Distribution and Feeding Models [PDF]
Pharmaceutics, 2020 The present paper reports a thorough continuous powder blending process design of acetylsalicylic acid (ASA) and microcrystalline cellulose (MCC) based on the Process Analytical Technology (PAT) guideline.
Martin Gyürkés +10 more
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Understanding the Residence Time Distribution in a Transient Inline Spiking System: Modeling, Experiments, and Simulations [PDF]
Membranes, 2023 A transient inline spiking system is a promising tool for evaluating the performance of a virus filter in continuous operation. For better implementation of the system, we performed a systematic analysis to understand the residence time distribution (RTD)
Minsun Hwang +2 more
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The impact of turbulence models on the simulation of residence time distribution in a multichamber ozone contactor [PDF]
Water Supply, 2021 The flow and tracer transport in an ozone contactor is simulated by using computational fluid dynamics. The standard k- model, RNG k- model, realizable k- model and SST k- model are used to describe turbulence.
Shijian Peng +3 more
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Investigations Concerning the Residence Time Distribution of Twin-Screw-Extrusion Processes as Indicator for Inherent Mixing [PDF]
Pharmaceutics, 2018 Over recent years Twin-Screw-Extrusion (TSE) has been established as a platform technology for pharmaceutical manufacturing. Compared to other continuous operation, one of the major benefits of this method is the combination of several unit operations ...
Jens Wesholowski +2 more
doaj +2 more sources
Heat Transfer and Residence Time Distribution in Plug Flow Continuous Oscillatory Baffled Crystallizers [PDF]
ACS Omega, 2021 Naomi E. B. Briggs +5 more
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Effect of propeller use on residence time distribution (rtd) in single-screw cam-flow rice semolina extrusion [PDF]
BIO Web of ConferencesThe influence of the speed of the feeding (Nf) and main (Nw) screw, the moisture content of the material (W) and the temperature of the die (Tm) on the average residence time (t) and the Peclet number (Pe) in single-screw extrusion of rice semolina using
Chalamov Yanush +4 more
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