Results 71 to 80 of about 215,638 (342)

Preparation and application of macromolecules with a fluorescence effect in polymer processing

Designed Monomers and Polymers, 2019
In this study, 9-anthracenemethyl methacrylate (AMMA) and styrene (St) as monomers and benzoyl peroxide as an initiator were used to synthesize P(St-co-AMMA), a macromolecule tracer with a fluorescence effect, via free radical copolymerization.
Meng-Di Chen, Guo Zhang, Shi-Chang Chen, Xian-Ming Zhang, Wen-Xing Chen   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Residence time distribution in the Scalable Agitated Baffle Reactor (SABRe)

, 2021
An in-depth examination of the residence time distribution properties of the Scalable Agitated Baffle Reactor ...
Stoli Chem
core   +1 more source

Mathematical Modeling and Design of Parboiled Paddy-Impinging Stream Dryer Using the CFD-DEM Model

Foods
Impinging stream dryers (ISDs) are effective for removing moisture from particulate materials because of the complex multiphase transport of air particles in ISDs.
Thanit Swasdisevi, Wut Thianngoen, Somkiat Prachayawarakorn   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Residence Time Distribution of Particles in a Screw Feeder: Experimental and Modelling Study

, 2015
Experiments were conducted to investigate the effects of screw speed and screw feeder inclination on the residence time distribution (RTD) of particles in a screw feeder via a pulse stimulus response technique.
Huo, Chaofei, Song, Wenli, Chuigang Fan, Chaofei Huo, Ping Feng, Weigang Lin, Wenli Song, Fan, Chuigang, Lin, Weigang, Feng, Ping   +9 more
core   +1 more source

Impact of residence time distributions in reacting magnesium packed-beds on Grignard reagent formation – Pump-induced flow behaviour in non-reacting magnesium beds (part 1)

, 2023
Grignard reagent formation in continuously operated magnesium packed-bed reactors can be influenced by finetuning the residence time distribution within the magnesium packing.
Michael, Maskos, Dirk, Ziegenbalg, Gabriele, Menges-Flanagan, Eva, Deitmann   +3 more
core   +1 more source

A New Approach for Modelling Residence Time Distribution in a Co-rotating Twin Screw Extruder

CHIMIA, 2001
A model to determine the residence time distribution (RTD) in a co-rotating twin screw extruder is proposed. The method couples a thermomechanical approach with a chemical engineering approach and allows us to obtain the RTD without a fitting ...
Arnaud Poulesquen, Bruno Vergnes, Philippe Cassagnau, Alain Michel   +3 more
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source