Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Semi-markov model of processing requests to the cloud storage
This paper presents a semi-Markov model as an important part of the computer-aided manufacturing and a modular system of cloud storage, which affects the functioning of the whole process. The residence times of the system in states and the probability of
Zamoryonov Mikhail +3 more
doaj +1 more source
Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier +3 more
wiley +1 more source
Subject-specific factors affecting particle residence time distribution of left atrial appendage in atrial fibrillation: A computational model-based study. [PDF]
Sanatkhani S +6 more
europepmc +1 more source
Residence Time Distribution of A Tubular Reactor
Most flow reactors are neither ideal plug flow nor continuous stirred tank reactors. This makes it difficult in accounting for actual conversion obtained from such reactors thus causing much concern to the industrialists especially Chemical Engineers. The extent of departure from the two ideal limits of flow reactors remained unclear until the concept ...
Minister E. Obonukut, Perpetua G. Bassey
openaire +1 more source
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source
Residence time distribution in RO channel
Abstract Residence time distribution (RTD) in a commercial Filmtec™ BW30-400 RO channel is determined using Computational Fluid Dynamics (CFD) and correlated with the Exponentially Modified Gaussian (EMG) model. The RTD, cumulative function of RTD, and flushing dynamics in RO channels are shown to be different from the analytical solutions derived ...
openaire +1 more source
The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti +5 more
wiley +1 more source
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang +23 more
wiley +1 more source
Development and Use of a Residence Time Distribution (RTD) Model Control Strategy for a Continuous Manufacturing Drug Product Pharmaceutical Process. [PDF]
Hurley S +4 more
europepmc +1 more source

