Results 41 to 50 of about 187,683 (302)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Material Transport Characteristics in Planetary Roller Melt Granulation

open access: yesPharmaceutics, 2023
Melt granulation for improving material handling by modifying particle size distribution offers significant advantages compared to the standard methods of dry and wet granulation in dust reduction, obviating a subsequent drying step. Furthermore, current
Tom Lang   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Residence time distribution and flow pattern modeling of oilseeds in a pilot screw press☆

open access: yesOilseeds and fats, crops and lipids, 2020
Mechanical expression is widely applied for oil recovery from oilseeds using continuous screw presses. Despite significant recent advances in the field of press design and automation, it remains difficult to predict the press performances based on the ...
Bogaert Laurine   +2 more
doaj   +1 more source

An improved model of continuous leaching systems using segregation approach [PDF]

open access: yesInternational Journal of Mining and Geo-Engineering, 2020
In this study, a simplified dissolution model has been developed to evaluate the performance of continuous leaching reactors. The model considers continuous reduction of the surface area of particles using the distribution of their size and residence ...
Abdolrahim Foroutan   +3 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Design and Development of Mathematical Model for Static Mixer [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2016
A numerical model for simulating Residence Time Distribution (RTD) of turbulent flows in helical static mixers is proposed and developed to improve the understanding of static mixers.
Akila Rajamanickam, Krishnaswamy Balu
doaj  

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

An attainable region perspective on the role of residence time distribution in ball milling

open access: yesSouth African Journal of Chemical Engineering, 2020
The effect of material flow through a ball mill on the efficient production of particles was explored using the attainable region framework. The target efficiency was the production of floatable particles of size between 300 μm and 75 μm upon expending ...
François K. Mulenga
doaj   +1 more source

Experimental simulation of salt transport in hierarchically nested groundwater flow systems

open access: yes地质科技通报, 2022
Groundwater age and groundwater residence time contain important information about groundwater circulation and evolutionary processes, and have been widely used in the study of groundwater circulation patterns in basins.In this paper, we simulated a ...
Hong Niu   +5 more
doaj   +1 more source

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