Results 151 to 160 of about 9,613 (261)

Ionization enhancement in radio-frequency plasma thrusters with applied static magnetic fields. [PDF]

Sci Rep
Lin Y, Hu P, Liu J, Qiang Y, Ren K, Cui L, Kang H.   +6 more
europepmc   +1 more source

Molecular Simulation of Functionalized Covalent Organic Framework Membranes for Inorganic Salt Separation

Advanced Theory and Simulations, EarlyView.
Six functionalized TpPa‐based covalent organic frameworks (COFs) are characterized using nonequilibrium molecular dynamics simulations to assess water permeance and salt rejection. The TpPa‐SO3H COF membrane achieves the highest sodium sulfate rejection (>98%) while maintaining relatively high water permeance compared to commercial nanofiltration ...
Grace Wei, Anand Narayanan Krishnamoorthy, Ganesh Sivaraman, Lauren Valentino   +3 more
wiley   +1 more source

Development of Practical Low-Volume Screening Method and Pharmacokinetic Simulation of Levofloxacin-Loaded Nanofiber Inserts for Sustained Ocular Therapy. [PDF]

Pharmaceutics
Abboud HA, Zelkó R, Kazsoki A.
europepmc   +1 more source

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

Advanced Science, EarlyView.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu, Weixia Xuan, Song Cao, Huayun Jia, Qian Wu, Xiaowu Tan, Qijie Wang, Xiaojun Li, Lisha Ding, Yaru Xiong, Meiyun Zhao, Longcheng Zheng, Yunzhu Xi, Jianhua Tan, Rong Li, Xulong Zhang, Wenjie Liu, Xu Wu   +17 more
wiley   +1 more source

Feasibility study of coke combustion and energy exergy analysis in the De-Coke process of cracking furnaces in olefin unit. [PDF]

Sci Rep
Moshtagh M, Azari A, Hoseinpour M, Fatehi R, Ghadyanlou F, Karami R, Rasul M, Akrami M.   +7 more
europepmc   +1 more source

Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface

Advanced Science, EarlyView.
This study identifies a cancer‐specific interaction between CD47 and integrin αvβ3 that facilitates immune evasion. A rationally designed peptide, PSFL‐NK13, disrupts this axis, enhancing macrophage‐mediated phagocytosis and suppressing tumor growth without inducing anemia.
Peng‐Cheng Yu, Chen‐Xi Yue, Wen‐Zhong Dong, Cui‐Yun Hao, Yi‐Fan Qiao, Di Liu, Xin Zhang, Qi Zhan, Jia‐Bao Yao, Dong‐Ping Wang, Peng Cao, Ying‐Zhe Fan, Ye Yu   +12 more
wiley   +1 more source

Reduced Shear Stress and Longer Blood Flow Time Occur in Both Severe Focal and Mild Diffuse LAD Lesions: Angiograms Alone Don't Always Reveal Their True Impact on Blood Flow. [PDF]

Pathophysiology
Rigatelli G, Zuin M, Mileva N, Vassilev D, Marchese G, Hiso E, Bertolini A, Bilato C.   +7 more
europepmc   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Microfluidic Concentration Manipulation via Controllable AC Electroosmotic Flow. [PDF]

Micromachines (Basel)
Lv J, Pei Y, Sun J.
europepmc   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source