Results 251 to 260 of about 3,320,969 (355)

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early‐Onset Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning   +18 more
wiley   +1 more source

Improving Family Medicine Residency Training in Women's Health-Related Procedures at a Community Hospital. [PDF]

open access: yesCureus
Azhar E   +10 more
europepmc   +1 more source

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

open access: yesAdvanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li   +7 more
wiley   +1 more source

Neurology Residency Training in 2022: Insights from the American Academy of Neurology's Resident Survey. [PDF]

open access: yesNeurol Educ
Emmert BE   +6 more
europepmc   +1 more source

AI‐Directed 3D Printing of Hierarchical Polyurethane Foams

open access: yesAdvanced Science, EarlyView.
Digitally guided direct ink writing, combined with AI‐generated design, enables the fabrication of hierarchical polyurethane foams with tunable multiscale porosity. This approach produces architected foams featuring interconnected open‐cell networks and tailored mechanical properties, advancing the development of adaptive, high‐performance materials ...
Dhanush Patil   +15 more
wiley   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu   +6 more
wiley   +1 more source

Examining the perception of residency training among Nigerian medical students: a nationwide pilot survey. [PDF]

open access: yesBMC Med Educ
Aderinto N   +15 more
europepmc   +1 more source

Uncertainty‐Quantified Primary Particle Size Prediction in Li‐Rich NCM Materials via Machine Learning and Chemistry‐Aware Imputation

open access: yesAdvanced Science, EarlyView.
This study demonstrates a machine learning framework that predicts the primary particle size of Lithium‐rich Nickel‐Cobalt‐Manganese (Li‐rich NCM) materials from synthesis conditions, even with incomplete literature data. By combining chemistry‐aware imputation with uncertainty‐quantified modeling, it identifies sintering temperature and time as ...
Benediktus Madika   +6 more
wiley   +1 more source

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