Results 131 to 140 of about 530,821 (311)

The impact of accessibility on residential choice - empirical results of a discrete choice model [PDF]

Transport in general, and accessibility of people, jobs and services in particular, is assumed to have an important impact on the residential choice behavior of households. After all, the amount of activities that can be deployed by the household members,
Berry Blijie
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Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Effect of the Norfolk Southern Train Derailment on House Prices in East Palestine, OH

Journal of Sustainable Real Estate
In February 2023, a Norfolk Southern (NS) train derailed in East Palestine Ohio. Several rail cars crashed off the tracks, releasing hazardous chemicals into two local creeks.
Robert A. Simons, Spenser J. Robinson, Daniel J. Simons   +2 more
doaj   +1 more source

Annual report (Arizona. Residential Utility Consumer Office)

, 2003
RUCO is an advocate of residential ratepayer interests before the Arizona Corporation Commission. We have been actively engaged in complex rate case litigations and additional line-siting and corporate certification applications, and played central ...

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Models of general practitioner services in residential aged care facilities [PDF]

, 2015
Describes different models for general practice care for patients in residential aged care facilities. Background Provision of timely and high-quality general practitioner (GP) services to patients in residential aged care facilities (RACFs) is ...
Richard Reed
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Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

'Nae too bad' : job satisfaction and staff morale in Scottish residential child care

, 2005
In 2003, the National Children's Bureau and the Social Education Trust published a report - Better Than You Think -on staff morale, qualifications and retention in residential child care in England (Mainey, 2003a; Mainey,2003b).
, Scottish Government (Funder), Kendrick, Andrew, Avan, Ghizala, Milligan, Ian   +3 more
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Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Optimisation and Operation of Residential Micro Combined Heat and Power (μCHP) Systems [PDF]

, 2012
In response to growing concerns regarding global warming and climate change, reduction of CO2 emissions becomes a priority for many countries, especially the developed ones such as the UK.
SHANEB, OMAR,ALI
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