Results 131 to 140 of about 734,738 (302)
Advanced Science, EarlyView.This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren +5 more
wiley +1 more source
What works in residential care: making it work
Scottish Journal of Residential Child Care, 2002 What works in residential care is complex. The quality of practice does not just depend on how care workers operate with, and on behalf of, the young people they look after.
Lesley Archer
doaj +1 more source
Avoiding admissions : the most cost effective delivery of acute care to residents of aged-care facilities in the Hutt Valley : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Business Studies in Management at Massey University [PDF]
, 2004 The highest annual costs of health care occur in the last one to two years of life. The most expensive part of health care provision during this period is aged-residential care.
Turner, Nicola Nell
core
Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair
Advanced Science, EarlyView.This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar +9 more
wiley +1 more source
Historical abuse in residential child care in Scotland 1950 -1995 [PDF]
, 2007 This is a systemic review: it's about systems - the systems of laws, rules and regulations (the regulatory framework) that governed residential schools and children's homes.
Hawthorn, Moyra +4 more
core +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv +8 more
wiley +1 more source
ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy
Advanced Science, EarlyView.A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou +9 more
wiley +1 more source
Quality of residential aged care: the consumer perspective [PDF]
This paper discusses concerns about the quality of care in a minority of residential aged care facilities, and puts forward strategies to address them. Executive summary: Over 222,000 people received permanent residential aged care services in 2012 with ...
core
Advanced Science, EarlyView.A deep comprehension of biomolecular phenomena at interfaces is significant with their fundamental and practical importance. Our experimental and theoretical investigations reveal that specific amino acids (glutamic acid and aspartic acid) exhibit an orientational coupling with liquid crystals, which can recognize and optically report the interfacial ...
Yena Choi +10 more
wiley +1 more source