Results 41 to 50 of about 4,683,185 (280)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

On the shoulders of giants (part two): an inspirational woman

open access: yesScottish Journal of Residential Child Care, 2008
This is the second paper based on the keynote speech given by Keith White at the SIRCC conference on 7th June 2007. In the first paper (White, 2007) he identified a few of the historically significant figures in residential child care and discussed the ...
Keith White
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Editorial Vol1 no1

open access: yesScottish Journal of Residential Child Care, 2002
On behalf of the Scottish Institute for Residential Child Care (SIRCC) and the Advisory Board, I am delighted to be welcoming you to the first issue of the Scottish journal of Residential Child Care. We very much hope that you enjoy this new contribution
Andrew Kendrick
doaj   +1 more source

Care versus treatment: reflections on residential child care in Scotland

open access: yesScottish Journal of Residential Child Care, 2023
'Residential treatment for adolescents' is a term used in the United States to describe something simultaneously similar to and completely different than residential child care in Scotland.
Laura Steckley
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane   +19 more
wiley   +1 more source

A qualitative study of support for young people who self-harm in residential care in Glasgow

open access: yesScottish Journal of Residential Child Care, 2004
A recent study found that 39 per cent of young people in residential care in Scotland had self-harmed compared to 18 per cent of young people living with their birth parents and 14 per cent of young people in foster care (Meltzer, Lader, Corbin, Goodman &
Judith Piggot   +3 more
doaj   +1 more source

Different sizes, similar challenges: Out of home care for youth in Germany and the Netherlands [PDF]

open access: yesPsychosocial Intervention, 2014
While there is a large difference in the number of young inhabitants in the Netherlands and Germany, their child protection frameworks are quite similar. In both countries, child protection services are mainlyfocused on youth aged 0 to 18 and regulations
Annemiek T. Harder   +4 more
doaj   +1 more source

Comparative Costs of Home Care and Residential Care [PDF]

open access: yesThe Gerontologist, 2004
This paper reports on Canadian research that examined the cost effectiveness of home care for seniors as a substitute for long-term institutional services.Two Canadian cities were included in the research: Victoria, British Columbia, and Winnipeg, Manitoba.
Neena L, Chappell   +4 more
openaire   +2 more sources

Temporal Divergence of True and False Alarms in Pediatric Nocturnal Seizure Monitoring

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
The early‐morning surge in false seizure alarms supports exploring time‐ or state‐dependent detection thresholds to reduce false detections. ABSTRACT Seizure detection devices can improve the safety of children with epilepsy, yet high false alarms limit their clinical applicability.
Mohammad Shahbakhti   +6 more
wiley   +1 more source

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