Results 261 to 270 of about 29,239,926 (346)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Restage Transurethral Resection in the Evaluation of T1 High-Grade Bladder Tumor. [PDF]

open access: yesCureus
Ahmed S   +7 more
europepmc   +1 more source

Cost-Effectiveness Analysis of Trastuzumab-Emtansine as Adjuvant Therapy for HER2-Positive Early Breast Cancer with Residual Invasive Disease in Colombia. [PDF]

open access: yesJ Health Econ Outcomes Res
Samacá-Samacá D   +6 more
europepmc   +1 more source

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