Results 121 to 130 of about 17,083 (261)

Atomic-Scale Mechanisms of Nanoscale Material Removal in FeCrNiCoCu High-Entropy Alloys: Coupled Effects of Crystallography, Grain Size, and Composition. [PDF]

Nanomaterials (Basel)
Ling X, Fu P, Li Y, Zhou Z, Li Z.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Evaluation and implementation of an independent Kilovoltage X-ray-based imaging platform for carbon ion radiotherapy. [PDF]

J Appl Clin Med Phys
Guo Y, Liu Z, Zhu Q, Cai M, Cai H, Liu R, Zhang Q, Xu Z.   +7 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Relationship between body segment movements and center of pressure shifts during trunk lean movements while sitting in healthy adults. [PDF]

Front Rehabil Sci
Liu B, Uehara S, Yuasa A, Ota H, Ushizawa K, Otaka Y.   +5 more
europepmc   +1 more source

Residual Quantization in Displacement Coding of Dynamic Meshes

IEICE Transactions on Information and Systems
NISHIMURA, Hitoshi, KATO, Haruhisa, KAWAMURA, Kei   +2 more
openaire   +1 more source

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Buckling and Post-Buckling Behaviour of a Carbon Fibre-Reinforced Polymer Stiffened Panel: A Numerical and Experimental Study. [PDF]

Polymers (Basel)
Sellitto A, Russo A, Zarrelli M, Vinti V, Trinchillo L, Perugini P, Riccio A.   +6 more
europepmc   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Experimental Study and Numerical Modeling of Inter-Pass Forging in Wire-Arc Additive Manufacturing of Inconel 718. [PDF]

Materials (Basel)
Smetannikov OY, Permyakov GL, Neulybin SD, Ovchinnikov IP, Oskolkov AA, Trushnikov DN.   +5 more
europepmc   +1 more source