Results 141 to 150 of about 19,346 (217)

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Physiological and Intestinal Microbiota Analyses Offer Insights into the Analysis of Differential Residual Feed Intake in Jian Carp (<i>Cyprinus carpio</i> var. <i>Jian</i>). [PDF]

Animals (Basel)
Jiang G, Zhang Y, Kamunga EM, Feng W, Xu Y, Li J, Zhang Z, Tang Y.   +7 more
europepmc   +1 more source

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Differential lipid metabolism in beef cattle: A comparative study of high and low residual feed intake bulls. [PDF]

Anim Nutr
Yi X, Yi S, Wang J, Ye B, Zhu X, Meng Q, Wu H, Zhou Z.   +7 more
europepmc   +1 more source

Perspective: Hollow Core Optical Fibres for Ultraviolet and Visible Wavelengths

Advanced Science, EarlyView.
Hollow core optical fibres bypass material constraints that limit optical fibres at ultraviolet and visible wavelengths. However, their challenging fabrication has limited their development, and significant gains in performance remain possible. In this perspective we outline approaches to enable the next generation of fibres for shorter wavelengths ...
Robbie Mears, Kerrianne Harrington, Jonathan C. Knight, William J. Wadsworth, James M. Stone, Tim A. Birks   +5 more
wiley   +1 more source

Effects of residual feed intake divergence on the productive performance, egg quality, meat quality, and gut microbiome in native chickens. [PDF]

Poult Sci
Wan Y, Ma R, Qi R, Liu W, Li J, Zhou L, Li Y, Li Y, Liu Z, Zhao W, Liu P, Li Y, Zhan K.   +12 more
europepmc   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Impact of residual feed intake on jejunal tight junction morphology and gene expression in slow-growing Korat chickens. [PDF]

Poult Sci
Kongthungmon S, Pengsanthia S, Kamkrathok B, Kaewsatuan P, Molee W, Molee A.   +5 more
europepmc   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Residual feed intake in late-laying hens: immune function, metabolic efficiency, and feed utilization dynamics. [PDF]

Front Vet Sci
Gao Z, Mao Z, Xuan L, Ma G, Wu Y, Xu G.
europepmc   +1 more source