Results 51 to 60 of about 582,501 (263)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Estimating Residual Native Kidney Urea Clearance in Hemodialysis Patients With and Without 24-Hour Urine Volume

Kidney Medicine, 2019
Rationale & Objective: Quantification of residual native kidney function is rarely performed in patients receiving hemodialysis. Methods of estimating residual kidney urea clearance that use commonly available laboratory and clinical data, with or ...
Andrew I. Chin, Vishwa Sheth, Jeehyoung Kim, Heejung Bang   +3 more
doaj   +1 more source

Residual Pneumoperitoneum Volume and Postlaparoscopic Cholecystectomy Pain

Anesthesiology and Pain Medicine, 2014
Gasretention in the peritoneal cavity plays an important role in inducing postoperative pain after laparoscopy, which is inevitably retained in the peritoneal cavity.The aim of this study was to detect the relation between the volume of residual gas and severity of shoulder and abdominal pain.In this Prospective study 55 women who were referred for ...
Sabzi Sarvestani, Amene, Zamiri, Mehdi
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Impact of gastric volume on sleeve gastrectomy outcomes using 3D CT volumetry

The Egyptian Journal of Radiology and Nuclear Medicine
Background Sleeve gastrectomy is an effective bariatric procedure; however, postoperative outcomes vary among patients. Residual gastric volume has been proposed as an anatomical factor influencing weight loss and surgical success.
Noha Essam, Khaled Mohamed Moghazy, Ahmed Abdelfatah Sabry, Mohsen Ahmed Abdelmohsen   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The Effect of Body Position on Gavage Residual Volume of Gastric in Intensive Care Units Patients

نشریه پرستاری ایران, 2018
Background & Aim: Malnutrition is experienced by most of the intensive care unit patients, which causes poor prognosis and worsens the disease. Gastric residual volume represents the status of food tolerate.
J Rezae, H Kadivarian, A Abdi, M Rezae, K Karimpour, S Rezae   +5 more
doaj  

Urinary Dysfunctions and Post-Void Residual Urine in Typical and Atypical Parkinson Diseases

Journal of Parkinson’s Disease, 2018
Background: Urinary dysfunction is relatively common, however, is often underestimated and diagnosed by subjective questionnaires in patients with Parkinsonism.
Yang-Hyun Lee, Jee-Eun Lee, Dong-Woo Ryu, Yoon-Sang Oh, Kwang-Soo Lee, Sung-Hoo Hong, Joong-Seok Kim   +6 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source