A Scalable and Resource‐Efficient Pipelined p‐Computer for Probabilistic Ising Machines
(a) Block diagram of the portfolio optimization problem: given M assets, the goal is to determine the optimal weights w that maximize the expected return (based on the mean historical assets return u), while minimizing the risk, quantified by the assets covariance matrix S.
Deborah Volpe +9 more
wiley +1 more source
A Bio-Inspired Authenticated Key Exchange Binding AlphaFold2 Protein Geometry to Ephemeral Elliptic-Curve Diffie-Hellman. [PDF]
Alabdulatif A +4 more
europepmc +1 more source
Revealing Hidden Raman Signatures Through Attention‐Based Spectral Unmixing
Weak Raman signatures are recovered from background‐dominated spectra using a transformer‐based, reference‐free spectral unmixing AI framework. Self‐attention reconstructs substrate contribution directly from mixed data, enabling reliable extraction of previously inaccessible vibrational features.
Dmitriy A. Poteryayev +9 more
wiley +1 more source
Mapping of dynamic allostery within p38 alpha kinase via network analyses and NMR spectroscopy. [PDF]
Roy Acharyya S +3 more
europepmc +1 more source
ABSTRACT Background Biologics and endoscopic sinus surgery (ESS) treat refractory chronic rhinosinusitis with nasal polyposis (CRSwNP), but direct comparisons are lacking. We synthesized efficacy and subgroup data across randomized controlled trials (RCTs) of biologics and ESS.
Arun Chakravorty +13 more
wiley +1 more source
OTalign: optimal transport alignment for remote protein homologs using protein language model embeddings. [PDF]
Kim M, Bae H, Jo G, Kim K, Yoo J, Joo K.
europepmc +1 more source
Fragment-Based Discovery of Potent RNA-Competitive Inhibitors of the DEAH-Box RNA Helicase DHX8. [PDF]
Read BJ +39 more
europepmc +1 more source
Free-Energy Landscapes of HBV Hexamer Closure Reveal Key Structural Features of the Transition. [PDF]
Fan Z +4 more
europepmc +1 more source
ABSTRACT Metal corrosion causes significant economic losses and safety hazards, underscoring the urgent need for effective, environmentally friendly corrosion inhibitors. In this study, an organic–inorganic composite inhibitor, chitosan–glucose–BN (CS–GL–BN) was developed to protect Q235 mild steel in a 3.5‐wt% NaCl solution.
Shanjun Xu +4 more
wiley +1 more source
Molecular requirements for PLK1 activation by T-loop phosphorylation. [PDF]
Esposito-Verza A +9 more
europepmc +1 more source

