Results 101 to 110 of about 302,155 (312)

Production of Lipolytic Enzymes Using Agro-Industrial Residues

open access: yesChemical Engineering Transactions, 2017
Lipase (E.C.3.1.1.3) is a versatile and key enzyme in various bioprocesses involving the esterification and transesterification reactions for biodiesel generation. However, the production and recovery of enzymes is very expensive and often constitute an obstacle to wide use in bioprocesses.
Pinotti L.M.   +5 more
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Formulation development and microstructure analysis of a polymer modified bitumen emulsion road surfacing : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Product Development at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2000
The purpose of this research was to develop a formulation for a polymer modified bitumen emulsion road surfacing product called microsurfacing to a mid-scale prototype stage.
Forbes, Allan R
core  

Flammability behaviour of wood and a review of the methods for its reduction [PDF]

open access: yes, 2013
Wood is one of the most sustainable, aesthetically pleasing and environmentally benign materials. Not only is wood often an integral part of structures, it is also the main source of furnishings found in homes, schools, and offices around the world.
Hull, T Richard, Lowden, Laura
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Iowa Innovators, June 2011 [PDF]

open access: yes, 2011
The “Iowa Innovators” series is a joint project of the Iowa Newspaper Association and the Iowa Department of Economic Development (IDED). The series is an outgrowth of an idea from member INA publishers.

core  

Recovery and reuse of discontinuous carbon fibres by solvolysis: Realignment and properties of remanufactured materials [PDF]

open access: yes, 2016
Discontinuous carbon fibre tows were recovered after solvolysis of an aeronautic type composite made with RTM6 epoxy resin. A Sohxlet extraction method was used to quantify the organic residue on the fibre tows and showed that less than 3 wt% was ...
Bailleul, Bailleul Jean-Luc   +4 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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