Results 41 to 50 of about 85,478 (264)
Furfural, a versatile platform compound, is produced from the hydrolysis of pentose (hemicellulose) in lignocellulosic biomass. The manufacturing of furfural results in the production and accumulation of cellulose- and lignin-rich furfural residue ...
Rui Li +6 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Treatment of carbon residue from aluminum electrolysis cell using Na2CO3
Carbon residue in aluminum electrolytic cell is a kind of hazardous waste produced during the smelting and production process of the aluminum industry. Approximately 10 kg of carbon residue is produced for every ton of primary aluminum produced.
Cheng LIANG +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Crop residues activity against the free-living stages of small ruminant nematodes
The nematicidal effect of different organic materials was evaluated in order to develop a non-chemical alternative soil treatment for control of the free-living stages of small ruminant gastrointestinal nematodes.
Hévila Oliveira Salles +12 more
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Chinese medicine is widely used in disease prevention and control, and a lot of Chinese medicine residue is produced in China every year. If these residues are not properly disposed of, they will cause damage to the environment and waste resources.
ZHOU Xin-hong +6 more
doaj
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Synthesis of microfibrillated cellulose from solid residue of seaweed processing industry and its applications in alginate-based hydrogels for papain enzyme carriers [PDF]
The seaweed processing industry generates cellulose-rich solid residues. Cellulose, a natural polymer, exhibits advantageous physical properties when employed as a scaffold or filler in specific matrices.
Hastuti Novitri +7 more
doaj +1 more source

