Results 221 to 230 of about 1,104,642 (331)

Structural analysis of antigenic variation and adaptive evolution of the H5N1 neuraminidase gene. [PDF]

PLoS Comput Biol
Adegbaju MS, Owo-Odusi O, Wirtz ET, Morenikeji OB, Ojurongbe O, Thomas BN.   +5 more
europepmc   +1 more source

Modelling Matured mRNA for Gene Expression Using Residue Number System

Joshua Apigagua Akanbasiam, Kwame Osei Boateng, Daniel Kuyoli Ngala   +2 more
openalex   +1 more source

A Proposed Architecture for Residue Number System based 1D 5/3 Discrete Wavelet Transform using Filter Bank and Lifting Scheme

, 2014
Uttam NarendraThakur, Souvik Saha, Anandarup Mukherjee   +2 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Water Accelerates in the Hydration Shell of the N- and C-Terminal Domains of α-Synuclein in the Presence of NaCl. [PDF]

J Phys Chem B
Koehler SJ, Vaissier Welborn V.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Prodigy protein: Python package for zero-shot protein engineering using protein language models. [PDF]

BMC Bioinformatics
Massett M, Carr A.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Achieving high precision in analog in-memory computing systems. [PDF]

Npj Unconv Comput
Mannocci P, Larelli G, Bonomi M, Ielmini D.   +3 more
europepmc   +1 more source

Magnetic Arithmetic Module for Pulse-Train Signal Processing Based on Residue Number System

, 1981
Mamoru Miura, S. Chiba, Junichi Shida, Tatsuo Higuchi   +3 more
openalex   +2 more sources