Solvent Reorganization in Stabilized Protein-Polymer Conjugates Visualized by Two-Dimensional Infrared and Nuclear Magnetic Resonance Spectroscopy. [PDF]
JACS AuMaia R +4 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Positive Selection Targeted Primate Genes that Encode Transposable Element Repressors. [PDF]
Genome Biol EvolCagliani R +6 more
europepmc +1 more source
The Allosteric Regulation of the DNA-Binding Domain of p53 by the Intrinsically Disordered C-Terminal Domain. [PDF]
Pharmaceuticals (Basel)Ning S +5 more
europepmc +1 more source
Corncob Returning Enhances Soil Fertility and Rhizosphere Microbiome Functions to Improve Growth and Nutrient Uptake of <i>Eleutherococcus sessiliflorus</i> in Cold Agroecosystems. [PDF]
Biology (Basel)Liu Q +8 more
europepmc +1 more source
β‑Arrestin-Mediated Activation of Chemokine Receptor CCR7 by Human β‑Defensin‑3 Drives Oral Squamous Cell Carcinoma Progression. [PDF]
JACS AuKinanti NP, Chang CC, Lai XY, Hsu HJ.
europepmc +1 more source
The Role of the Electronic Structure during Protein Folding through Electron Density-Based Quantum Chemical Descriptors. [PDF]
ACS OmegaRocha-Santos A +3 more
europepmc +1 more source