Results 181 to 190 of about 1,372,061 (319)

Scientific Opinion of the EFSA Panel on Plant Protection Products and their Residues (PPR), Guidance on the use of probabilistic methodology for modelling dietary exposure to pesticide residues

, 2012
<p>The European Food Safety Authority (EFSA) asked the Panel on Plant Protection Products and theirResidues to provide guidance on methodology for performing probabilistic dietary exposureassessment of single or multiple active substances, as a ...
C. Vleminckx, EFSA Panel on Plant Protection Products and their Residues (PPR)   +1 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

<i>De novo</i> grafted coiled-coil peptides as p53/<i>h</i>DM2 inhibitors. [PDF]

RSC Chem Biol
Spain F, Gimenez D, Acevedo-Jake AM, Mylemans B, Brooks NJ, Korona B, Huang DT, Edwards TA, Leney AC, Itzhaki L, Woolfson DN, Wilson AJ.   +11 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Evolutionary analysis of transcription elongation factors reveals conserved and lineage-specific regulatory domains. [PDF]

PLoS Biol
Francette AM, Grover A, Clark N, Arndt KM.   +3 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Integrative Computational Prediction Strategy for Antibody-Antigen Binding: A Case Study on Interleukin-1 Beta. [PDF]

J Chem Inf Model
Aygen ME, Uyar A.
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

On the distribution of power residues and non-residues.

Journal für die reine und angewandte Mathematik (Crelles Journal), 1972
openaire   +2 more sources

Screening Atg11, a central organizer of yeast selective autophagy, for residues involved in the Atg11-Atg9 interaction. [PDF]

MicroPubl Biol
Sherpa CD, Woghiren P, Leonello E, Abdel-Khalek M, Schuessler BJ, Vermaas JV, Backues SK.   +6 more
europepmc   +1 more source