Results 101 to 110 of about 67,312 (295)

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Resiliency in Child–Caregiver Dyads and the Impact on Health Outcomes in Sickle Cell Disease

Children
Background/Objectives: Resiliency is critical in coping with stressors associated with chronic health diseases. Sickle cell disease (SCD) is a chronic blood disorder in which familial psychosocial functioning impacts disease outcomes.
Jessica A. Zavadil, Melissa Azul, Brian D. Carpenter, Cecelia Calhoun   +3 more
doaj   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl, Marika C. Möller, Lindsay Wilson, Anne Vik, Toril Skandsen, Jonas Stenberg, CENTER‐TBI participants and investigators   +6 more
wiley   +1 more source

Body Composition Benefits Diminish One Year After a Resistance Training Regimen in Breast Cancer Patients, Although Improvements in Strength, Balance, and Mobility Persist

Journal of Functional Morphology and Kinesiology
Objectives: Resistance training can improve body composition and physical function during and after breast cancer treatment and improve quality of life.
Colin E. Champ, Jared Rosenberg, Chris Peluso, Christie Hilton, Rhyeli Krause, Alexander K. Diaz, David J. Carpenter   +6 more
doaj   +1 more source

PENGARUH FAKTOR EKOLOGI TERHADAP RESILIENSI REMAJA

Jurnal Ilmu Keluarga dan Konsumen, 2017
Youth nowadays are increasingly required to have a resiliency in order to prevent disturbance in their developmental task, quality of life, and their future.
Euis Sunarti, Intan Islamia, Nur Rochimah, Milatul Ulfa   +3 more
doaj   +1 more source

Resilience: for and against [PDF]

Postgraduate Medical Journal, 2015
Fashions in medical education rise and fall like fashions in drug treatment. A new idea like “leadership” comes along, educators take it up with enthusiasm, institutions start to offer training in the subject, and research money becomes available to explore its effectiveness. After a while, people start to express scepticism about the idea. Researchers
openaire   +2 more sources

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu, Tianxue Chen, Wei Jin, Weifeng Jin, Haitong Wan   +4 more
wiley   +1 more source

Grip strength as a surrogate measure of strength, functional, and metabolic parameter increases in breast cancer survivors undergoing an exercise regimen

Scientific Reports
Grip strength, a surrogate for quantifying strength, correlates with function and longevity. However, this relationship is less clear in women with breast cancer.
Colin E. Champ, Chris Peluso, Christie Hilton, Jared Rosenberg, Rhyeli Krause, Alexander K. Diaz, David J. Carpenter   +6 more
doaj   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source