Results 51 to 60 of about 4,348,911 (323)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
EXTRACTION AND SEPARATION OF SOME ACTIVE COMPOUNDS IN ERUCA SATIVA AND STIUDY IT'S BIOLOGICAL ACTIVITY [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2014 This study aimed to sperat and extract of some active compounds in Eruca sativa .It included identificaion and determination of active compounds their percentages in the leaves,stem and seeds,like(Tannine, Glycosides,Alkaloids,Saponins,Resins,Flavonoids ...
MOHAMMED HAMEED – AL MOHAMMDI +1 more
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Indonesian Journal of Chemistry, 2019 The uranium sorption from productive solutions containing chloride ions using anion-exchange resins was investigated. The VPAE ion exchanger had the highest values of the sorption capacity, which for the experiment in the static mode was 13 kg U m-3, and
Svetlana Titova +3 more
doaj +1 more source
Electrochemically treated lignin in phenolic resins for plywood panels
Sustainable Chemistry for the Environment, 2023 In achieving the European Union's goal of making Europe the first climate-neutral continent by 2050, the scientific community is striving to develop processes and products that are technologically and economically sustainable to replace/substitute fossil-
Electra Papadopoulou +6 more
doaj +1 more source
Studies of the biological and therapeutic effects of argentine stingless bee propolis [PDF]
, 2018 Meliponids are native bees of the Americas, characterized by having no sting (ANSA). Some live in the Yunga forests of northern Argentina, a place rich in a diversity of this type of bees of which at least thirty-three species may be found. Propolis is a
Brodkiewicz, Ivana Yanina +5 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Thermoset polymers containing bio-based renewable resources
eXPRESS Polymer Letters, 2009 Editorial ...
doaj +1 more source
The Iraqi Journal of Veterinary Medicine, 2009 This study included evaluation of inhibition activity of watery and oily extracts of Rosmerinus officinalis plant on some pathogenic microorganisms like Salmonella typhi، Escheichia coli ، Staphylococcus aureus ، Klebsiella pneumoniae، Aeromonas ...
Auroba M.S. Ibrahim
doaj +1 more source