Results 51 to 60 of about 2,678,573 (309)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Characterising native plant resins from Australian Aboriginal artefacts using ATR-FTIR and GC/MS [PDF]

, 2014
Resin use by Australian Aborigines has been documented in ethnographic accounts across the continent and is also evident from archaeological and anthropological artefacts.
McCollum, A. J., Matheson, C. D.
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Analytical methods applied to diverse types of Brazilian propolis

Chemistry Central Journal, 2011
Propolis is a bee product, composed mainly of plant resins and beeswax, therefore its chemical composition varies due to the geographic and plant origins of these resins, as well as the species of bee.
Marcucci Maria, Barbosa da Silva Cunha Ildenize, Sawaya Alexandra   +2 more
doaj   +1 more source

Pinoresinol stimulates keratinocyte proliferation and downregulates TNF‐α secretion in peripheral blood mononuclear cells: An experimental in vitro study

Health Science Reports, 2023
Background and Aims Natural coniferous resins are used in traditional medicine for the treatment of skin wounds. Coniferous wood resins (“callus” resin) are a mixture of abietic (resin) acids, lignans such as pinoresinol, and p‐coumaric acid.
Elias Haapakorva, Hannu Raunio, Atte vonWright, Ilkka Harvima   +3 more
doaj   +1 more source

Exploring factors in honey bee choice of antimicrobial plant resins [PDF]

, 2017
Faculty advisor: Marla SpivakThis research was supported by the Undergraduate Research Opportunities Program (UROP).Graber, Lea. (2017). Exploring factors in honey bee choice of antimicrobial plant resins.
Graber, Lea
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Effect of Storage Time on the Dimensional Stability of 3D Printed Dental Model Resins

Dentistry 3000
The aim of this study was to evaluate the effect of storage-induced aging on the dimensional stability of two 3D printed resins, a plant-based and a conventional dental model resin.
Mohammed M. Sadoon, Aliaa Wameedh Al-Omari, Omar Abdul Mohsin Sheet   +2 more
doaj   +1 more source

Separation and Purification of Two Saponins from Paris polyphylla var. yunnanensis by a Macroporous Resin

Molecules, 2022
An effective method for separating and purifying critical saponins (polyphyllin II and polyphyllin VII) from a Paris polyphylla var. yunnanensis extract was developed in this study which was environmentally friendly and economical.
Xiaoya Zhang, Junli Wu, Long Qin, Guangxi Wang, Ping Li, Anmin Yu, Aizhong Liu, Rui Sun   +7 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source