Results 91 to 100 of about 1,885,146 (393)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Reappraisal of IgG subclass deficiencies: a retrospective comparative cohort study

Frontiers in Immunology
ObjectiveThe aim of the present study was to investigate the clinical spectrum of IgG subclass deficiencies (IgGSDs) and assess the relative clinical significance of diagnosing each specific IgGSD disorder as compared to the common variable ...
Damla Dogru, Yagmur Dogru, Faranaz Atschekzei, Faranaz Atschekzei, Abdulwahab Elsayed, Abdulwahab Elsayed, Natalia Dubrowinskaja, Diana Ernst, Torsten Witte, Torsten Witte, Torsten Witte, Vega Gödecke, Vega Gödecke, Georgios Sogkas, Georgios Sogkas   +14 more
doaj   +1 more source

A microfluidic magnetohydrodynamic pump based on a thermally bonded composite of glass and dry film photoresist

Micro and Nano Engineering, 2023
Miniaturized on-chip micropumps with no moving parts are intriguing components for advanced lab-on-chip systems. Magnetohydrodynamic pumping is one possibility but requires further research with respect to microsystems design and fabrication.
Raschid Azizy, Henning Otto, Jörg König, David Schreier, Christoph Weigel, Christian Cierpka, Steffen Strehle   +6 more
doaj  

Rounding of Negative Dry Film Resist by Diffusive Backside Exposure Creating Rounded Channels for Pneumatic Membrane Valves

Micromachines, 2015
Processing of dry film resist is an easy, low-cost, and fast way to fabricate microfluidic structures. Currently, common processes are limited to creating solely rectangular channels.
Philipp Frank, Sebastian Haefner, Georgi Paschew, Andreas Richter   +3 more
doaj   +1 more source

Bld10/Cep135 stabilizes basal bodies to resist cilia-generated forces

Molecular Biology of the Cell, 2012
Basal bodies act as anchorage sites for cilia and resist forces generated by ciliary beating. Bld10/Cep135 is a basal body assembly factor. A novel role is found for Bld10 in stabilizing basal bodies to resist cilia-generated forces.
Brian A Bayless, T. Giddings, M. Winey, C. Pearson   +3 more
semanticscholar   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Who Gets to Resist?

Politikon
This paper examines contested definitions of terrorism and resistance, analyzing how the US and India instrumentalize such labels to suppress dissent and monopolize violence.
Mohammad Amaan Siddiqui
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Modal analysis and dynamic stresses for acoustically excited shuttle insulation tiles [PDF]

Improvements and extensions to the RESIST computer program developed for determining the normalized modal stress response of shuttle insulation tiles are described.
Ogilvie, P. L., Ojalvo, I. U.
core   +1 more source