MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Successive superconducting transitions in Ta2S2C studied by electrical resistivity and nonlinear ac magnetic susceptibility [PDF]
, 2007 Masatsugu Suzuki +4 more
openalex
RF SOI CMOS technology on 1st and 2nd generation trap-rich high resistivity SOI wafers
, 2016 Babak Kazemi Esfeh +6 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
ADVANCE-ID bacterial and fungal infections review: antimicrobial resistance research updates: Summary of clinical trials and implementation studies, March-April 2026. [PDF]
JAC Antimicrob ResistMo Y, Manesh A, Wang J, Paterson DL.
europepmc +1 more source
A method to adjust the impedance of the transmission line in a Multi-Strip Multi-Gap Resistive Plate Counter [PDF]
, 2017 D. Bartoş +4 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Detection of OXA-23 and OXA-58 in <i>Proteus mirabilis</i> by immunochromatographic assays. [PDF]
Microbiol SpectrNoster-Schrader J +7 more
europepmc +1 more source