Results 41 to 50 of about 475,541 (366)

Resistance in Vancomycin-Resistant Enterococci

Infectious Disease Clinics of North America, 2020
Serious infections owing to vancomycin-resistant enterococci have historically proven to be difficult clinical cases, requiring combination therapy and management of treatment-related toxicity. Despite the introduction of new antibiotics with activity against vancomycin-resistant enterococci to the therapeutic armamentarium, significant challenges ...
William R, Miller, Barbara E, Murray, Louis B, Rice, Cesar A, Arias   +3 more
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Antibiotic Susceptibility Profiles of Bacterial Isolates Recovered from Abscesses in Cattle and Sheep at a Slaughterhouse in Algeria

Microorganisms
Abscesses represent the most prominent emerging problem in the red meat industry, leading to great economic constraints and public health hazards. Data on etiological agents present in these purulent lesions in Algeria are very scarce.
Chahrazed Yousfi, Saoussen Oueslati, Dina Daaboul, Delphine Girlich, Alexis Proust, Chafia Bentchouala, Thierry Naas   +6 more
doaj   +1 more source

Pengembangan Desain Tekstil 3 Budaya dengan Tema Etnik Kontemporer

Dinamika Kerajinan dan Batik: Majalah Ilmiah, 2016
Kegiatan membuat celup rintang dilakukan banyak negara di dunia. Sejarah asal-usul teknik ini diperkirakan berasal dari Asia dan berkembang ke wilayah India, bersambung ke wilayah Malaysia.
Isti Kartika
doaj   +1 more source

Comparison of Three Expanded-Spectrum Cephalosporin Hydrolysis Assays and the NG-Test CTX-M Multi Assay That Detects All CTX-M-Like Enzymes

Diagnostics, 2022
Rapid detection of expanded-spectrum cephalosporins (ESC) hydrolysing enzymes is crucial to implement infection control measures and antibiotic stewardship.
Camille Gonzalez, Christian Moguet, Arnaud Chalin, Saoussen Oueslati, Laurent Dortet, Stéphanie Simon, Hervé Volland, Thierry Naas   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Undetectable Production of the VIM-1 Carbapenemase in an Atlantibacter hermannii Clinical Isolate

Frontiers in Microbiology, 2021
The differential expression of VIM-1 in Atlantibacter hermannii WEB-2 and Enterobacter hormaechei ssp. hoffmannii WEB-1 clinical isolates from a rectal swab of a hospitalized patient in France was investigated. A.
Delphine Girlich, Rémy A. Bonnin, Rémy A. Bonnin, Alexis Proust, Thierry Naas, Thierry Naas, Thierry Naas, Laurent Dortet, Laurent Dortet, Laurent Dortet   +9 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Evaluation of the Reveal^® AST (SPECIFIC) for Antimicrobial Susceptibility Testing from Positive Blood Culture Spiked with Carbapenem-Resistant Isolates

Pathogens
As bloodstream infections and associated septic shock are common causes of mortality in hospitals, rapid antibiotic susceptibility testing (AST) performed directly on positive blood cultures is needed to implement an efficient therapy in clinical ...
Delphine Girlich, Agnès B. Jousset, Cécile Emeraud, Inès Rezzoug, Reece Burwell, Pragya Singh, Paul A. Rhodes, Thierry Naas, Rémy A. Bonnin, Laurent Dortet   +9 more
doaj   +1 more source