Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Dietary nitrate supplementation does not improve resistance exercise performance in resistance-trained women. [PDF]
Brennan SN +17 more
europepmc +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Combined aerobic and resistance exercise improves glucose metabolism and insulin resistance in children and adolescents with overweight or obesity: a meta-analysis. [PDF]
Qi Z, Xin X, Liu Q, Xu X, Guo Y.
europepmc +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Evidence of histamine release in response to both aerobic and resistance exercise: histamine metabolites as biomarkers. [PDF]
Gibson BM +5 more
europepmc +1 more source
The effect of intradialytic resistance exercise on physical function and dialysis adequacy in patients on maintenance hemodialysis. [PDF]
Boukadida R +12 more
europepmc +1 more source
The effects of biological sex on fatigue during and recovery from resistance exercise. [PDF]
Nuckols GL +3 more
europepmc +1 more source
Acute Effects of Beetroot Supplementation on Resistance Exercise Performance in Physically Active Men. [PDF]
Rodrigues MY +8 more
europepmc +1 more source

