Results 301 to 310 of about 5,101,401 (348)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Effects of autoregulated and non-autoregulated blood flow restriction on vastus medialis oblique responses during low-load resistance exercise. [PDF]

Front Sports Act Living
Moghaddam M, Rabel MC, Werner T, Rolnick N.   +3 more
europepmc   +1 more source

Data Sheet 1_Effects of acute caffeine intake on muscular power during resistance exercise: a systematic review and meta-analysis.docx

Yuchun Xiao (323072), Li Ding (16240), Zhenbo Xu (392294), Jue Liu (538235), Li Guo (171454), Matthew J. Barnes (14135087), Yinhang Cao (22381828), Olivier Girard (409080)   +7 more
openalex   +1 more source

Determining the role of exercise-induced heat in resistance exercise conditioning

, 2020
Benjamin Smith
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Aerobic and resistance exercise-regulated phosphoproteome and acetylproteome modifications in human skeletal muscle. [PDF]

Nat Commun
Pataky MW, Heppelmann CJ, Sevits KJ, Asokan AK, Kumar AP, Klaus KA, Dasari S, Kunz HE, Strub MD, Robinson MM, Coon JJ, Lanza IR, Adams CM, Nair KS.   +13 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Combined aerobic and resistance exercise training restores perivascular adipose tissue function in the thoracic aorta of rats with heart failure. [PDF]

Clin Sci (Lond)
Fontes MT, Dos Reis Costa DEF, Dardi P, Paula SM, Couto GK, de Castro É, Rossoni LV.   +6 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

The effect of dietary nitrate supplementation on resistance exercise performance: A dose-response investigation. [PDF]

Eur J Appl Physiol
Tan R, Lincoln IG, Paniagua KK, Foster JM, Wideen LE, Gerardo RT, Ornelas NJ, Tchaprazian I, Li J, Egiazarian M, Rowland SN, Bailey SJ, Pennell A.   +12 more
europepmc   +1 more source