Results 221 to 230 of about 1,259,159 (318)

Assessment of aminoglycosides and β-lactam resistance genes among uropathogens; a prospective-cross sectional study. [PDF]

BMC Urol
Khan J, Basharat N, Sadiq A, Ali S, Khan H, Ali I, Bogale A, Al-Emam A, Hassan HM.   +8 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Fitness effects of antimicrobial resistance genes in changing environments

Escudero JA, Hipólito A, García-Pastor L, von Strempel A, Weiss A, Sastre-Dominguez J, Vergara E, Alvarez J, Fuentes-Hernández A, Peña-Miller R, Millan AS, Stecher B.   +11 more
europepmc   +1 more source

Investigating the distribution of antibiotic resistance genes in relation to bacterial, fungal, and functional diversity in a hay field. [PDF]

Microbiol Spectr
de Santana CO, Spealman P, Vispo C, Gresham D, Saccomanno S, LaFratta CN, Jain SS, Dungan RS, Perron GG.   +8 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Unraveling the activity of phage-carrying antibiotic resistance genes in constructed wetlands. [PDF]

Front Cell Infect Microbiol
Zhao Q, Wang D, Lin H, Zhou T, Zhang J, Shang J, Cai D, Sun Y, Hu Z, Zhang J.   +9 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Molecular Profiles and Antimicrobial Resistance Genes in Bacterial Isolates from Chronic Rhinosinusitis Patients. [PDF]

Pathogens
Osman A, Ghenea AE, Mogoanta CA, Enache I, Bucătaru A, Cioboată R, Georgescu M, Bălășoiu AT, Zlatian OM.   +8 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source