Results 91 to 100 of about 810,262 (267)
IntroductionObesity is a public health problem worldwide, and body composition assessment is a very important diagnostic tool. Bioelectrical Impedance Analysis (BIA) is a fast, non-invasive, relatively low-cost, and user-friendly technique; however, to ...
Kalina Veruska Da Silva Bezerra Masset +7 more
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Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
IntroductionBreed-specific characterization of uterine hemodynamics is essential for improving reproductive monitoring and management in indigenous Bos indicus cattle; however, systematic Doppler reference data across the estrous cycle remain limited ...
Uttam Kumar Sahu +17 more
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Clinical Significance of Diagnostic Images in the Evaluation of Cervical Cancer
Background. The problems of diagnostics and treatment of cervical cancer (CC) currently remain relevant due to the increase in morbidity and high mortality from this disease, including patients of reproductive age.
N. V. Nudnov +3 more
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Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Introduction. To stop obstetric bleeding, organ-preserving surgical methods are used, one of which is ligation of three-layered uterine vessels. The effectiveness of organ-preserving methods comprises up to 94 %.
N. M. Inoyatova, D. T. Kayumova
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