Results 91 to 100 of about 9,801,758 (307)
_M. tuberculosis_ interactome analysis unravels potential pathways to drug resistance [PDF]
, 2008 Drug resistance is a major problem for combating tuberculosis. Lack of understanding of how resistance emerges in bacteria upon drug treatment limits our ability to counter resistance.
Nagasuma Chandra, Karthik Raman
core
Serotype and antibiotic resistance profiles across relevant literature.
, 2019 Serotype and antibiotic resistance profiles across relevant literature.
Lauryn R. Keeler (8149680) +6 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Civil Resistance Comparative Perspectives on Nonviolent Struggle
, 2015 In the past quarter century the world has witnessed dramatic social and political transformations, due in part to an upsurge in civil resistance. There have been significant uprisings around the globe, including the toppling of communist regimes in ...
Schock, Kurt
core
Reflecting the Justice-Seeking “Roshanaee (Illumination) Movement” in the Poems of Contemporary Afghan Poets [PDF]
ادبیات پایداریIn recent years, concurrent with the culmination of injustice and systematic discrimination in Afghanistan, the poetry of justice-seeking has also soared.
Moslem Nadalizadeh, Besmillah Borhani
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Analysis of the Components of Resistance Literature in the Works of Syrian Poets and Writers [PDF]
ادبیات پایداریResistance literature in Syria has long been considered one of the main literary branches due to its proximity to the occupied territories and the Quds issue, which has been the main concern of the Islamic world and the world's freedom seekers for many ...
Niloofar Ansari
doaj +1 more source