Results 201 to 210 of about 2,325,348 (267)

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

open access: yesSmart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang   +8 more
wiley   +1 more source

Additive Manufacturing of Hot‐Work Tool Steel by In Situ Alloying Using Laser Powder Bed Fusion and Directed Energy Deposition—Strategies to Improve Chemical Homogeneity

open access: yessteel research international, EarlyView.
To support future alloy development a powder mixture is processed by laser additive manufacturing. The powder mixture containing Mo‐ and W‐rich tracers is processed by powder bed fusion using single and double laser exposure and by directed energy deposition which provides drastically enlarged melt pools.
Felix Großwendt   +2 more
wiley   +1 more source

A Comparative Study of Directed Energy Deposition‐Arc and Casting: Enhancing Mechanical and Thermal Properties of Hot‐Work Tool Steels

open access: yessteel research international, EarlyView.
The study investigates the influence of DED‐Arc/M versus casting on the microstructure and material properties of X40CrMoV5‐1 (AISI H13) hot‐work tool steel. DED‐Arc/M yields finer microstructures, superior mechanical strength, and ductility, but slightly reduced thermal conductivity.
Ulf Ziesing   +4 more
wiley   +1 more source

Microstructure and Mechanical Properties of Dissimilar Friction Stir Welded T-Lap Joints Between AA5083 and AA7020. [PDF]

open access: yesMaterials (Basel)
Torzewski J   +6 more
europepmc   +1 more source

Tailoring Laser Powder Bed Fusion and Post‐Processing Parameters for JIS SKD61 Tool Steels: Surface Roughness, Microstructure, and Mechanical Properties

open access: yessteel research international, EarlyView.
Laser powder bed fusion of JIS SKD61 tool steel is systematically optimized using a Taguchi design and ANOVA. Hatch spacing and layer thickness are identified as dominant parameters controlling surface roughness and tensile strength. Subsequent tempering at 600°C improves microstructural stability and mechanical performance, enabling high‐density SKD61
Masrurotin Masrurotin   +4 more
wiley   +1 more source

Microstructure Characterization of Bending Effects in 304L Stainless Steel Cladded with Low‐Alloy Steel Weld

open access: yessteel research international, EarlyView.
Prebending of 304L/Q345R cladded plates significantly alters the subsequent weld thermal cycle and modifies the local interfacial microstructure. Combined electron backscatter diffraction (EBSD) and microscopy analysis demonstrates that deformation twinning, martensitic transformation, and defect initiation are concentrated at the trimaterial junction,
Ali Fahem   +2 more
wiley   +1 more source

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