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Drug-resistant chronic migraine: the Italian GON project

Neurological Sciences, 2012
Chronic daily headache is a major problem due to severe disability and high socio-economic costs. In the last years, some trials have shown potential benefit from new therapeutic approach by occipital neurostimulation techniques, already applied with some success for the treatment of chronic cluster headache.
A. Proietti Cecchini   +4 more
openaire   +3 more sources

Prophylactic sodium valproate therapy in patients with drug-resistant migraine

Methods and Findings in Experimental and Clinical Pharmacology, 1998
We assessed the efficacy of sodium valproate as a prophylactic agent in migraine headache. A prospective randomized study was conducted in adult patients who previously derived no significant benefit from most conventional prophylactic therapy for migraine.
K, Ghose, B, Niven
openaire   +2 more sources

Switching OnabotulinumtoxinA to Monoclonal Anti-CGRP Antibodies in Drug-Resistant Chronic Migraine

CNS Drugs, 2023
OnabotulinumtoxinA (BTX-A) and anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies (anti-CGRP mAbs) are approved drugs for chronic migraine (CM), a difficult-to-treat condition. Optimization of CM patient management by choosing the best options and determining appropriate time for switching or adding concomitant treatments are highly ...
Iannone, Luigi Francesco   +6 more
openaire   +2 more sources

Erenumab efficacy in highly resistant chronic migraine: a real-life study

Neurological Sciences, 2020
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Pensato U.   +9 more
openaire   +3 more sources

Chronic migraine in women is associated with insulin resistance: a cross‐sectional study

European Journal of Neurology, 2013
Background and purposeMigraine is a common neurological disorder. It can be divided into episodic migraine (EM) and chronic migraine (CM), based on headache frequency. Some studies have shown that insulin sensitivity is impaired in migraine; moreover, hypertension, diabetes and obesity are common in patients with CM. The aim of this study was to assess
Fava A   +12 more
openaire   +2 more sources

The Long-Term Treatment of Drug-Resistant Migraine With the Modified Atkins Ketogenic Diet: A Single-Center, Retrospective Study

open access: yesNutrients
Despite advances in pharmacological therapies, migraine patients are often drug resistant. Further therapeutic options in this field are, therefore, desirable. Recent studies have highlighted the efficacy of ketogenic diet (KD) on improving migraine, but
Lorenzo A Calò   +2 more
exaly   +2 more sources

Erenumab for the treatment of chronic resistant migraine

Medicina Clínica (English Edition), 2022
Almudena, Layos-Romero   +2 more
openaire   +2 more sources

Determinants of glucose metabolism and the role of NPY in the progression of insulin resistance in chronic migraine

Cephalalgia, 2017
Background Chronic migraine has a well-documented association with increased insulin resistance and metabolic syndrome. The hypothalamus may play a role in the progression of insulin resistance in chronic migraine through the regulation of orexigenic peptides such as neuropeptide Y.
Zeynep Oşar, Siva   +8 more
openaire   +3 more sources

Don’t Miss Migraines in Patients with Drug-Resistant Epilepsy

Neuropediatrics, 2021
F. Dannenberg   +4 more
openaire   +1 more source

FHM3 in familial hemiplegic migraine is more resistant to mutation than FHM1 and FHM2

Journal of the Neurological Sciences, 2009
Familial hemiplegic migraine (FHM) is a rare subtype of migraine with aura and transient hemiplegia. CACNA1A (FHM1) gene, the ATP1A2 (FHM2) and the SCN1A (FHM3) are reported for their correlation to FHM. Here, a bioinformatics analysis was done to study the risk positions for mutation within the amino acid sequence of the three mentioned molecules.
openaire   +2 more sources

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