Results 31 to 40 of about 1,033,768 (122)

CGRP antibody therapy in patients with drug resistant migraine and chronic daily headache: a real-world experience

open access: yesThe Journal of Headache and Pain, 2021
Background Calcitonin gene-related peptide (CGRP) (receptor) antibodies (erenumab, fremanezumab and galcanezumab) are increasingly used in prophylactic treatment of migraine.
Armin Scheffler   +6 more
doaj   +1 more source

Associations between stress and migraine and tension-type headache: Results from a school-based study in adolescents from grammar schools in Germany [PDF]

open access: yes, 2011
Introduction: Stress is considered the major contributor to migraine and tension-type headache in adolescents. Previous studies have focused on general stressors, whereas the aim of the present study was to investigate associations between individuals ...
Straube, Andreas   +15 more
core   +1 more source

Effects of galcanezumab on acute medication use and health care resource utilization in treatment-resistant migraine: results from randomized, double blind, placebo-controlled clinical trial, conquer

open access: yesHeadache Medicine, 2020
Introduction Acute headache medication use (AHM) and health care resource utilization (HCRU) in patients with protocol-defined treatment-resistant migraine treated with galcanezumab (GMB).
Anna Ambrosini   +6 more
doaj   +1 more source

Real‐world evidence following a mandatory treatment break after a 1‐year prophylactic treatment with calcitonin gene‐related peptide (pathway) monoclonal antibodies

open access: yesBrain and Behavior, 2022
Background Current German and European guidelines suggest migraine patients undertake a treatment break after 9 to 12 months of treatment with CGRP (pathway) monoclonal antibodies.
Michael Nsaka   +6 more
doaj   +1 more source

Botulinum Toxin as Preventive Treatment for Migraine: A Randomized Double-Blind Study [PDF]

open access: yes, 2009
Aim: To determine if botulinum toxin type A (BoNT-A) injections can reduce the frequency and severity of migraines. Methods: Patients (n = 127) were randomized to receive placebo or two doses of BoNT-A (Dysport (R)). The primary endpoint was reduction in
Toelle, Thomas   +13 more
core   +1 more source

Self-reported muscle pain in adolescents with migraine and tension-type headache [PDF]

open access: yes, 2012
Aim: To identify possible associations between muscular pain and headache in adolescents in a large population-based sample. Methods: Grammar school students were invited to fill in a questionnaire on headache and associated lifestyle factors.
Straube, Andreas   +9 more
core   +1 more source

Revisiting the expanded use of hyperbaric oxygen therapy for treatment of resistant migraines [PDF]

open access: yesMedical Gas Research, 2019
There are currently 13 indications approved by the U.S. Food and Drug Administration for use of hyperbaric oxygen therapy. The European Consensus Conference on Hyperbaric Medicine has 28 indications approved for its use. However, neither includes the use of hyperbaric oxygen therapy for neurological conditions such as migraines with aura.
Matera, David V   +2 more
openaire   +2 more sources

P/Q-type calcium-channel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine? [PDF]

open access: yes, 2002
The discovery of mis-sense mutations in the alpha1A subunit of the P/Q-type calcium channel in patients with familial hemiplegic migraine indicates the potential involvement of dysfunctional ion channels in migraine.
Goadsby, PJ   +11 more
core   +1 more source

Association of patent foramen ovale with epilepsy: A hospital‐based case–control study

open access: yesEpilepsia Open, 2023
Objective This study aimed to investigate the proportion of patent foramen ovale (PFO) in people with epilepsy (PWE) compared to controls without epilepsy and to assess whether PWEs with and without PFO exhibit distinctive clinical features. Methods This
Yusha Tang   +6 more
doaj   +1 more source

The Role of Galcanezumab in Migraine Prevention: Existing Data and Future Directions

open access: yesPharmaceuticals, 2021
Galcanezumab is a humanized monoclonal antibody blocking the calcitonin gene-related peptide (CGRP) pathway by targeting the CGRP. Data from four phase-3 randomized placebo-controlled clinical trials showed that galcanezumab is superior to placebo in ...
Panagiotis Gklinos, Dimos D. Mitsikostas
doaj   +1 more source

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