Results 201 to 210 of about 145,637 (315)

Comprehensive evaluation of gas-bearing properties in ultra-deep basement reservoirs based on an optimizable support vector machine. [PDF]

Sci Rep
Huang X, Tang J, Zhao J, Li J, Yin S, Feng S, Li H.   +6 more
europepmc   +1 more source

Resist!: Resisting Technology and the Technology of Resistance [PDF]

, 2020
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Improving Fabrication and Performance of Porous Silicon Electron Emission Devices via Functional Layer Resistivity Modulation. [PDF]

Nanomaterials (Basel)
Dong J, Huyan X, Luo F, Zhang G, Liu Q, Li Y, Hu T, Liu Y, Wang S, Yu W.   +9 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Influence of the Rapid Thermal Nitriding Process on the Properties of TiN Thin Films Obtained from TiO₂ Sol-Gel Layers. [PDF]

ACS Omega
Vallejo-Otero V, Crespo-Monteiro N, Valour A, Donnet C, Ollier N, Barnier V, Bleu Y, Gamet E, Jourlin Y.   +8 more
europepmc   +1 more source

Electromagnetic imaging reveals insufficient fluids to explain shallow megathrust creep at the Shumagin Gap. [PDF]

Nat Commun
Li Y, Naif S, Key K, Constable S, Evans RL, Shillington DJ, Bécel A, Cordell D.   +7 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Ternary Dimension-Synergistic Conductive Architecture Enabling High-Rate, Low-Temperature and Extended-Cycling Nickel-Rich NCA Lithium-Ion Batteries. [PDF]

Materials (Basel)
Li Z, Yang H, Xu M, Tian X.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source