Results 231 to 240 of about 9,486 (287)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Edge Transport in Haldane-Like Models with Quasi-Periodic Disorder. [PDF]

Commun Math Phys
Caragiulo F, Mastropietro V, Porta M.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Painlevé Kernels and Surface Defects at Strong Coupling. [PDF]

Ann Henri Poincare
François M, Grassi A.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Amyloïdose cutanée nodulaire localisée consécutive à des injections d’insuline chez une femme de 40 ans. [PDF]

CMAJ
Zhuang M, Vaziri M, Sandhu N.
europepmc   +1 more source

Exact hydrodynamic manifolds for the linear Boltzmann BGK equation I: spectral theory. [PDF]

Contin Mech Thermodyn
Kogelbauer F, Karlin I.
europepmc   +1 more source

Quantum tunneling and its absence in deep wells and strong magnetic fields. [PDF]

Proc Natl Acad Sci U S A
Fefferman CL, Shapiro J, Weinstein MI.
europepmc   +1 more source

Isolated steady solutions of the 3D Euler equations. [PDF]

Proc Natl Acad Sci U S A
Enciso A, Kepplinger W, Peralta-Salas D.
europepmc   +1 more source

Pricing of geometric Asian options in the Volterra-Heston model. [PDF]

Rev Deriv Res (Dordr)
Aichinger F, Desmettre S.
europepmc   +1 more source