Results 101 to 110 of about 20,153 (290)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Electronic Journal of Differential EquationsThis article concerns the optimal control and the approximate controllability for second order integro-differential equation with state-dependent delay and non-instantaneous impulses.
Abdelhamid Bensalem +3 more
doaj
Schr\"odinger operators on the half line: Resolvent expansions and the Fermi golden rule at thresholds [PDF]
, 2005 We consider Schr\"odinger operators $H=- \d^2/\d r^2+V$ on $L^2([0,\infty))$ with the Dirichlet boundary condition. The potential $V$ may be local or non-local, with polynomial decay at infinity.
Jensen, Arne, Nenciu, Gheorghe
core +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Difference families with applications to resolvable designs
Hiroshima Mathematical Journal, 1995 It is well known that difference families consisting of disjoint start blocks can be used in the construction of resolvable designs. The authors use sets of units in rings, for which the difference of any two of these units is again a unit (a well-known approach), to obtain such difference families and hence to construct some infinite series of ...
Kageyama, Sanpei, Miao, Ying
openaire +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Rate of convergence of attractors of reaction-diffusion equations with nonlinear boundary conditions
, 2020 This paper we study the rate of convergence of the asymptotic dynamics of reaction-diffusion equations with nonlinear Robin boundary conditions. We show how the rate of convergence of the global attractors can be affected by the variation of the ...
Bezerra, Flank David Moraes +1 more
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Approximation of inverse problems for fractional differential equations in abstract spaces
Alexandria Engineering JournalThis article focuses on approximating a fractional-order inverse problem (IP) for an abstract differential equation in a Hilbert space. The main tools to find out the results are fixed-point methods, the α-resolvent family, and optimal control (OC ...
Santosh Ruhil +3 more
doaj +1 more source