Results 151 to 160 of about 20,153 (290)

Pseudo Numerical Ranges and Spectral Enclosures. [PDF]

open access: yesComplex Anal Oper Theory, 2022
Gerhat B, Tretter C.
europepmc   +1 more source

Resolutions with families of resolving agents

open access: yes, 2002
Om de inhoud van dit proefschrift en de relevantie ervan te kunnen begrijpen, is het nodig eerst iets uit te leggen over de ruimtelijke structuur van moleculen. Veel moleculen kunnen voorkomen in zogenaamde spiegelbeeldvormen. Dit komt doordat deze moleculen een koolstofatoom (C-atoom) hebben waaraan vier verschillende groepen gebonden zijn.
openaire   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Impulsive fractional differential inclusions with infinite delay

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we apply Bohnenblust-Karlin's fixed point theorem to prove the existence of mild solutions for a class of impulsive fractional equations inclusions with infinite delay. An example is given to illustrate the theory.
Khalida Aissani, Mouffak Benchohra
doaj  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Nonlinear Stability in a Free Boundary Model of Active Locomotion. [PDF]

open access: yesArch Ration Mech Anal
Berlyand L, Safsten CA, Truskinovsky L.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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