Results 101 to 110 of about 8,783 (264)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Iterative Schemes for Finite Families of Maximal Monotone Operators Based on Resolvents

open access: yesAbstract and Applied Analysis, 2014
The purpose of this paper is to present two iterative schemes based on the relative resolvent and the generalized resolvent, respectively. And, it is shown that the iterative schemes converge weakly to common solutions for two finite families of maximal ...
Li Wei, Ruilin Tan
doaj   +1 more source

On the Spectral Form Factor for Random Matrices. [PDF]

open access: yesCommun Math Phys, 2023
Cipolloni G, Erdős L, Schröder D.
europepmc   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Formally self-adjoint quasi-differential operators and boundary-value problems

open access: yesElectronic Journal of Differential Equations, 2013
We develop the machinery of boundary triplets for one-dimensional operators generated by formally self-adjoint quasi-differential expression of arbitrary order on a finite interval.
Andrii Goriunov   +2 more
doaj  

Mining definitions in Kissat with Kittens. [PDF]

open access: yesForm Methods Syst Des, 2022
Fleury M, Biere A.
europepmc   +1 more source

Dynamics on Grassmannians and resolvents of cone operators

open access: yes, 2009
The paper proves the existence and elucidates the structure of the asymptotic expansion of the trace of the resolvent of a closed extension of a general elliptic cone operator on a compact manifold with boundary as the spectral parameter tends to ...
Gil, Juan   +2 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Solvable limit of ETH matrix model for double-scaled SYK

open access: yesJournal of High Energy Physics
We study the two-matrix model for double-scaled SYK model, called ETH matrix model introduced by Jafferis et al. [arXiv:2209.02131]. If we set the parameters q A , q B of this model to zero, the potential of this two-matrix model is given by the Gaussian
Kazumi Okuyama, Takao Suyama
doaj   +1 more source

Home - About - Disclaimer - Privacy