Results 81 to 90 of about 8,783 (264)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Norm estimates for functions of non-selfadjoint operators nonregular on the convex hull of the spectrum

open access: yesDemonstratio Mathematica, 2017
We consider a bounded linear operator A in a Hilbert space with a Hilbert-Schmidt Hermitian component (A − A*)/2i. A sharp norm estimate is established for functions of A nonregular on the convex hull of the spectrum. The logarithm, fractional powers and
Gil’ Michael
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Possibilities of optimization of postoperative analgeziya

open access: yesАмбулаторная хирургия, 2016
The place of nonsteroid resolvents (NPVS) in treatment of a postoperative pain syndrome is considered. Safety issues of a nimesutid in comparison with other NPVS are discussed.
N. V. Verlan
doaj  

Multi-interval Sturm–Liouville boundary-value problems with distributional potentials

open access: yesДоповiдi Нацiональної академiї наук України
We study the multi-interval boundary-value Sturm–Liouville problems with distributional potentials. For the corresponding symmetric operators boundary triplets are found and the constructive descriptions of all self-adjoint, maximal dissipative and ...
A. S. Goriunov
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Multi-interval dissipative Sturm–Liouville boundary-value problems with distributional coefficients

open access: yesДоповiдi Нацiональної академiї наук України
The paper investigates spectral properties of multi-interval Sturm–Liouville operators with distributional coefficients. Constructive descriptions of all self-adjoint and maximal dissipative/accumulative extensions in terms of boundary conditions are ...
A.S. Goriunov
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Compactness of the difference between the porous thermoelastic semigroup and its decoupled semigroup

open access: yesElectronic Journal of Differential Equations, 2015
Under suitable assumptions, we prove the compactness of the difference between the porous thermoelastic semigroup and its decoupled one. This will be achieved by proving the norm continuity of this difference and the compactness of the difference ...
El Mustapha Ait Benhassi   +3 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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