Results 61 to 70 of about 7,733 (263)

Achieving maximal speed of solution exchange for patch clamp experiments. [PDF]

PLoS ONE, 2012
BACKGROUND: Resolving the kinetics of agonist binding events separately from the subsequent channel gating processes requires the ability of applying and removing the agonist before channel gating occurs.
Jerónimo Auzmendi, Darío Fernández Do Porto, Carla Pallavicini, Luciano Moffatt   +3 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Multi-Level Buffering Services Based on Optical Packet Encoding of Composite Maximal-Length Sequences in a GMPLS Network

Applied Sciences, 2020
Generalized multi-protocol label-switching (GMPLS) provides packet-switching with multiple speeds and quality-of-services (QoSs). Packet buffering in GMPLS reduces packet loss by resolving the conflicts between packets requesting for a common channel ...
Kai-Sheng Chen, Wien Hong
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

On the Constant Partition Dimension of Some Generalized Families of Toeplitz Graph

Journal of Mathematics
The use of graph theory is prevalent in the field of network design, whereby it finds utility in several domains such as the development of integrated circuits, communication networks, and transportation systems. The comprehension of partition dimensions
Ali N. A. Koam, Ali Ahmad, Maryam Salem Alatawi, Adnan Khalil, Muhammad Azeem   +4 more
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Understanding and mathematical modelling of cellular resource allocation in microorganisms: a comparative synthesis

BMC Bioinformatics, 2021
Background The rising consensus that the cell can dynamically allocate its resources provides an interesting angle for discovering the governing principles of cell growth and metabolism.
Hong Zeng, Reza Rohani, Wei E. Huang, Aidong Yang   +3 more
doaj   +1 more source

Resolving the Steiner Point Removal Problem in Planar Graphs via Shortcut Partitions

, 2023
Manuscript not intended for publication.
Chang, Hsien-Chih, Conroy, Jonathan, Le, Hung, Milenkovic, Lazar, Solomon, Shay, Than, Cuong   +5 more
openaire   +2 more sources

Phylogenomic approaches untangle early divergences and complex diversifications of the olive plant family

BMC Biology, 2022
Background Deep-branching phylogenetic relationships are often difficult to resolve because phylogenetic signals are obscured by the long history and complexity of evolutionary processes, such as ancient introgression/hybridization, polyploidization, and
Wenpan Dong, Enze Li, Yanlei Liu, Chao Xu, Yushuang Wang, Kangjia Liu, Xingyong Cui, Jiahui Sun, Zhili Suo, Zhixiang Zhang, Jun Wen, Shiliang Zhou   +11 more
doaj   +1 more source