Results 211 to 220 of about 150,008 (260)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Optical coherence tomography biomarkers of posterior scleritis in different stages of the disease activity. [PDF]

open access: yesFront Ophthalmol (Lausanne)
Nayak S   +6 more
europepmc   +1 more source

Resolving short-term meteorological variability amplifies projected glacier loss and sea-level rise. [PDF]

open access: yesNat Commun
Van Tricht L   +7 more
europepmc   +1 more source

Advances in the Design and Functionality of a Compact Multi-Reflecting Time-of-Flight Mass Spectrometer. [PDF]

open access: yesRapid Commun Mass Spectrom
Wildgoose J   +7 more
europepmc   +1 more source

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