Results 261 to 270 of about 8,830,736 (317)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Characterization of the complete mitochondrial genome and phylogenetic analysis of <i>Tetraselmis marina</i> (Cienkowski) R.E.Norris, Hori & Chihara 1980. [PDF]

Mitochondrial DNA B Resour
Cheng C, Chen CH, Yang F.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

The SMC5/SMC6 complex is critical for resolving R-loop-induced transcription-replication conflicts. [PDF]

Nucleic Acids Res
Wu T, Li Y, Zhao Y, Bournique E, Ortega P, Nie M, Wang Y, Wang H, Buisson R, Hickson ID, Boddy MN, Wu X.   +11 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Docosahexaenoic acid supplementation inhibits monocyte exhaustion memory formation during sepsis. [PDF]

Inflamm Res
Caldwell BA, Wu Y, Ie S, Lucas A, Conacher B, Zhang Y, Razani B, Li L.   +7 more
europepmc   +1 more source

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz, Carl D. Langefeld, Mary E. Comeau, Miranda C. Marion, Tyler P. Behymer, Lee A. Gilkerson, Padmini Sekar, Weihong Yuan, Vivek Khandwala, Brady J. Williamson, Thomas Maloney, Achala Vagal, Pierce Boyne, Kari Dunning, Matthew L. Flaherty, Steven J. Kittner, Prachi Mehndiratta, Gunjan Y. Parikh, Michael L. James, David Roh, Fernando D. Testai, Farhaan S. Vahidy, James Thornton, Ranjit Bagga, Daniel Woo, Stacie L. Demel   +25 more
wiley   +1 more source

Comparing image quality of synchrotron and laboratory nano-CT scans: a round robin study. [PDF]

J Synchrotron Radiat
Wittl S, Zabler S, Fell J, Villanova J, Lhuissier P, Hildebrandt S, Herrmann HG.   +6 more
europepmc   +1 more source

Exploring the Relationship Between Diaphragmatic Ultrasound Parameters and Lipid Mediators in Chronic Obstructive Pulmonary Disease: A Case Control Study. [PDF]

Am J Mens Health
Jelassi W, Hedhli A, Hajtaeib S, Euchi K, Ben Fraj MK, Cheikhrouhou S, Ouahchi Y, Mjid M, Toujani S, Feki M, Dhahri B.   +10 more
europepmc   +1 more source

The impact of artificial intelligence on case-based learning during pre-clerkship education. [PDF]

Can Med Educ J
Chai GW, Murariu AC, Leung FH.
europepmc   +1 more source