Results 31 to 40 of about 73,737 (268)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Bound states of the discrete Schrodinger equation with compactly supported potentials
Electronic Journal of Differential Equations, 2019 The discrete Schrodinger operator is considered on the half-line lattice $n\in \{1,2,3,\dots\}$ with the Dirichlet boundary condition at $n=0$. It is assumed that the potential belongs to class $\mathcal{A}_b$, i.e. it is real valued, vanishes when n>
Tuncay Aktosun +2 more
doaj
Infrared Array With Circular Phosphorene Resonators in Square Unit Cells
IEEE Photonics JournalWe propose and theoretically investigate a new 2D structure consisting of monolayer phosphorene disk resonators in the unit cell of a square lattice.
Victor Dmitriev +3 more
doaj +1 more source
Oscillations in Arrays of Nonlinear Elements in the Scott Experiment
Моделирование и анализ информационных систем, 2015 Bifurcation analysis of dynamic system modeling the array of coupled ocillators in the experience of Scott are presented. The non-resonant cases are considered.
A. S. Bobok, S. D. Glyzin
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Frontiers in PhysicsWe consider the one-dimensional Dirac equation with the most general relativistic contact interaction supported on two points symmetrically located with respect to the origin.
Carlos A. Bonin +3 more
doaj +1 more source
Resonance Reconstruction in the MPD
Particles, 2021 The study of hadronic resonance production is an essential part of the physical programs of many heavy-ion experiments. Detailed measurement of the resonance properties is also foreseen in the future Multi-Purpose Detector (MPD) experiment at the NICA ...
Dmitry Ivanishchev +4 more
doaj +1 more source
On Education. Journal for Research and Debate, 2020 This essay addresses the relations between recent reassessments of critique in literary studies and current debates in the field of education. Drawing on the work of Hartmut Rosa, it argues for the relevance of “resonance” as an educational concept. Resonance is not an emotion but a relation: not a positive feeling but an often ambivalent experience of
openaire +2 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source