Results 31 to 40 of about 4,392 (262)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A Novel ZVS/ZCS Push-Pull LC Resonant DC-DC Converter for Energy Sources

open access: yesEnergies, 2023
In this paper, a novel soft switching push-pull LC resonant DC-DC converter for energy sources is presented. In a high step-up converter, the input of primary side possesses low voltage and high current, so the losses caused by the current account for ...
You-Kun Tai, Kuo-Ing Hwu
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Pulse-Amplitude-Modulation Full-Bridge Diode-Clamped Multilevel LLC Resonant Converter Using Multi-Neighboring Reference Vector Discontinuous PWM

open access: yesEnergies, 2022
A full-bridge diode-clamped multilevel LLC resonant converter suitable for power conversion systems that use high input voltage, such as railway vehicles, is proposed in this paper. In order to eliminate the voltage deviations of the capacitors connected
Min-Sup Song, Jae-Bum Lee
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

A Novel Wide Gain Range LLC Resonant Converter With Multiple Operating Modes

open access: yesIET Power Electronics
This paper proposes a novel LLC resonant converter featuring two completely identical resonant circuits. By adjusting the control strategy of primary‐side switches, the two resonant circuits can operate independently or in series, allowing the entire ...
Yihui Xia   +4 more
doaj   +1 more source

Hybrid Resonant Converter with Three Half-Bridge Legs for Wide Voltage Operation

open access: yesApplied Sciences, 2019
This paper studied a hybrid resonant converter with three half bridge legs for wide input voltage operation. Compared to the conventional resonant converters with narrow voltage operation, the presented converter can achieve wider voltage operation.
Bor-Ren Lin, Yong-Sheng Zhuang
doaj   +1 more source

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